The H1N1 influenza strain known as swine flu killed a 26-year-old Jordanian man on Sunday, Health Minister Abdullatif Wreikat said on Sunday.
"The 26-year-old died in hospital today in Irbid," in northern Jordan, Wreikat told state-run Petra news agency.
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"He was taken to the Princess Basma (public) Hospital three days ago suffering from severe pneumonia. Medical tests showed H1N1 infection, which led to the man's death."
H1N1 influenza has killed 25 people in Jordan in recent years.
In 2009, an H1N1 epidemic erupted in Mexico and spread into a worldwide pandemic that caused at least 17,000 deaths.
Spreading from live birds to humans through direct contact, the flu causes fever and breathing problems.