The US first lady will visit a school in Amman built with technical and financial support from the US Agency for International Development and plans to commend Jordan's "generosity and commitment to educating all children living within its borders," a statement said.
Due to the conflict in neighboring Syria, a number of Jordanian schools have welcomed Syrian students to their classrooms.
Signup to our newsletter and follow us on Facebook and Twitter!
Jordan is hosting more than 600,000 Syrian refugees, according to the UN High Commissioner for Refugees.
Obama will also visit the ancient city and archaeological site of Petra in Jordan, which President Barack Obama visited in 2013.
In Doha, the first lady will speak at the World Innovation Summit for Education.
She will also visit the US military's Al Udeid air base.